Well, it has finally happened. News this week of widespread and disruptive anti-vaccine protests at Canadian medical centres means that America’s destructive, self-defeating and totally nonsensical anti-vaccine movement has begun crossing the border. As a pediatrician, vaccine-scientist and parent of an adult daughter with autism and intellectual disabilities, I have had a front-row seat to America’s anti-vaccine movement for the last two decades. I’m also a lead target, and sometimes known as the ‘OG Villain’ for writing the book, Vaccines Did Not Cause Rachel’s Autism a few years back. When I learned of this, I had to Google it — OG means ‘original gangster.’ My gangster status has since accelerated,when our research group at Texas Children’s Hospital and Baylor College of Medicine developed a global health COVID-19 vaccine now being scaled for production in India and Indonesia.