Discussion posted by: David McNamara
Researchers at Tulane University School of Medicine have identified a gene that causes an aggressive form of breast cancer to rapidly grow. More importantly, they have also discovered a way to “turn it off” and inhibit cancer from occurring. The animal study results have been so compelling that the team is now working on FDA approval to begin clinical trials and has published details in the journal Scientific Reports. The team led by Dr. Reza Izadpanah examined the role two genes play in causing triple negative breast cancer (TNBC). TNBC is considered to be the most aggressive of breast cancers, with a much poorer prognosis for treatment and survival. Izadpanah’s team specifically identified an inhibitor of the TRAF3IP2 gene, proven to suppress the growth and spread (metastasis) of TNBC in mouse models that closely resemble humans.